The AI+ Library — byStraits Institute for Applied AI
AI+Libraryby Straits Institute for Applied AI
Catalogue/Tier 3 · Job Skills/Research & Media
AI+ Clinical Research & Evidence-Based Practice cover
T3-88 · Tier 3 · Job Skills

AI+ Clinical Research & Evidence-Based Practice

Find, Appraise and Apply Clinical Evidence with AI

The evidence is out there. Now you have a system to find it.

You know the evidence should be driving your clinical decisions — but finding and reading it feels like a second job. The PROBE Protocol (Problem, Retrieve, Oversight, Bridge, Embed) gives you a five-step AI-assisted system for turning any clinical question into an actionable answer. With 32 prompt templates, CASP-based appraisal guides, and a 90-day EBP action plan, this is the book that makes evidence-based practice feel like practice, not research. Built by an AI engineering firm for clinicians who know the evidence matters — and finally have a system to act on it.

Tier
Tier 3 · Job Skills
Category
Research & Media
Format
Guide
Updated
Q2 2026
Inside
  • 32 ready-made AI prompt templates: PICO formulation, database search strings, critical appraisal, statistical interpretation, patient communication
  • The PROBE Protocol — a five-step AI-assisted EBP cycle from clinical question to embedded practice change
  • CASP-based appraisal frameworks for RCTs, cohort studies, systematic reviews, and clinical guidelines
  • The PROBE Bridge Applicability Filter — five questions for translating trial evidence to your specific patients and setting
  • A 90-day EBP system-building plan with personal, team, and institutional tracks for any clinical role
Who this is for

Clinicians — doctors, nurses, physiotherapists, pharmacists, occupational therapists, dieticians, and other allied health professionals — at any career stage who need to find, read, and apply clinical research evidence in their daily practice. Typically trained in a profession but without a research background; reads occasional papers but struggles with volume, statistical language, and translating findings to specific patients.

Also for:Postgraduate clinical students (MBBCh, MSc, MPhil clinical programmes) who need to integrate EBP skills into clinical training; quality improvement leads and clinical educators designing EBP training programmes; junior researchers moving from bench or lab into clinical settings.

You’ll be able to
  • Formulate precise clinical questions using PICO/PICOS/SPIDER with AI assistance
  • Conduct targeted, AI-accelerated searches of clinical evidence databases
  • Critically appraise randomised trials, cohort studies, systematic reviews, and clinical guidelines for bias and validity
  • Interpret key statistical measures (NNT, RR, OR, confidence intervals) to judge clinical significance
  • Translate appraised evidence into practice decisions that account for local context, patient values, and clinical uncertainty
What’s inside
Diagnostic
How evidence-ready are you?
Chapter 1
AI in Evidence-Based Clinical Practice Right Now
Chapter 2
Formulating Clinical Questions
Chapter 3
AI-Assisted Evidence Search
Chapter 4
Critical Appraisal of Primary Studies
Chapter 5
Reading Systematic Reviews, Guidelines, and Meta-Analyses
Chapter 6
Understanding Statistics for Evidence Appraisal
Chapter 7
Translating Evidence to Your Clinical Context
Chapter 8
Navigating Uncertainty and Conflicting Evidence
Chapter 9
Communicating Evidence to Patients and Clinical Teams
Chapter 10
Building an Evidence-Based Practice System
Back matter
Skill Summary · Recommended Next Reads · Glossary · Tool Reference

Built by an AI engineering firm for clinicians who know the evidence matters — and finally have a system to act on it.

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How this was made

AI+ Clinical Research & Evidence-Based Practice is written by AI engineers who build production AI systems, then pressure-tested by professionals who apply the skill in their work. It is reviewed every six months and updated whenever the technology or regulation shifts.

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